If you plan to be seen as a professional artist and you have the tendency to post 100 pictures of your meals/pets/selfie with ‘funny’ filters every day then separate accounts. If your art is more of a hobby and/or if you post 1 non-art related picture every two weeks then no need to separate accounts.
What happens after 10k followers on Instagram?
Once you have 10k followers, Instagram will make it easier for you to get people to your website via Stories with the swipe up to link feature. Swipe up is the only way to get a direct link from your Instagram to your other web properties. And, it’s available in STORIES, if you have 10k followers.